Using serial section electron microscopy and petabyte-scale machine learning reconstruction, researchers have mapped tens of thousands of neurons and millions of synapses across an intact cortical hemisphere.
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Using serial section electron microscopy and petabyte-scale machine learning reconstruction, researchers have mapped tens of thousands of neurons and millions of synapses across an intact cortical hemisphere.
Neuroscience has reached a milestone comparable to the sequencing of the human genome. An international consortium of researchers has published the complete synaptic-resolution wiring diagram of a mammalian cortical column, revealing structural wiring principles that challenge longstanding dogmas.
Reconstructing Petabytes of Neural Tissue
The project sliced neural tissue into 30-nanometer sections, imaged them via automated electron microscopes, and deployed computer vision neural networks to trace axonal pathways and catalog over 150 million individual synapses.
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