Aging is increasingly recognized by biogerontologists not as an inevitable physical decay, but as a loss of epigenetic information. In groundbreaking longitudinal trials, scientists have successfully reversed biological age markers in cardiac and neural tissue using transient in-vivo expression of modified Yamanaka factors.
Restoring the Cellular Epigenetic Landscape
By pulsing the reprogramming factors for tightly controlled intervals, cells reset their DNA methylation patterns to a youthful state while preserving their differentiated cell identity, restoring youthful metabolic function and regenerative capacity.
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